Don addresses reports surrounding the tragic deaths of filmmaker Rob Reiner and his wife, Michelle, allegedly at the hands of their son, and sharply criticizes how the incident was politicized by pro-Trump commentators. He condemns the framing of the tragedy as a consequence of so-called “Trump Derangement Syndrome,” calling it dehumanizing, dishonest, and emblematic of a broader pattern in modern political discourse. Don argues that the real derangement lies with unwavering Trump supporters who, in his view, ignore corruption, misinformation, and economic harm while projecting blame onto critics. He pushes back against claims of a booming economy and restored global respect, pointing instead to persistent affordability issues, tariffs hurting middle-class Americans, and policies he credits to the Biden administration for stabilizing inflation. The segment closes with Don expressing frustration over the state of the country, voter regret among some Trump supporters, and his belief that the nation’s political and moral decline is being accelerated by grievance politics and personal loyalty over facts.